|
KMID : 0357119820040010001
|
|
Korean Journal of Immunology
1982 Volume.4 No. 1 p.1 ~ p.9
|
|
|
Agglutinating Antibodies to Propionibacterium acnes and Staphylococcus aureus in the Sera of Healthy Individuals and Inpatients with Underlyig Diseases
|
|
최철순/Choi, Chul Soon
곽병은/양용태/Kwak, Byung Eun/Yang, Yong Tae
|
|
|
Abstract
|
|
|
Both Propionibacteriwn acnes and Staphylococcus aureus are predominant normal flora of human skin. The existence of bight titres of "natural" antibodies both to P. acmes and S. aureus has been demonstrated. However, comparative measurement or analysis of correlation between these antibodies in the sera obtained from patients with underlying diseases has not been clarified. In this study, antibodies to P. aches and S. aureus in the sera of I07 healthy individuals and 64 inpatients of acute or chronic underlying diseases were measured and the correlation between these antibodies was analyzed.
In normal sera, antibody to S. aureus (5.79±2.06 log2) was higher than to P. acnes (4.78±1.50 log2) and the patients´ sera yielded similar results. A high correlation between antibodies to P. aches and S. aureus was found both in normal (r=0.47, p<0.00I) and patients´ sera (r=0.61, P<0.001), but no correlation between antibody to S. aureus and to S. epidermidis was observed.
In patients´ sera, a high antibody titres to S. aureus was found in sera from liver cirrhosis(7.66± 0.57 log2), osteomyelitis (6.36+2.00 log2) and hepatitis (6.50±1.50 log2), but no difference was observed between diabetes mellitus (5.00±1.00 log2) and healthy individuals (5.79±2.06 log2). Similarly, a high antibody titre to P. aches appeared in the sera of the patients with osteomyelities (5.72±1.60 log2) but there was no difference between diabetes mellitus (5.00±1.00 log2) and healthy individuals (4.78±1.50 log2), whereas either low or no antibody was detectable in the sera of other patients´ sera as well hepatoma and tuberculosis.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|
|